Types and Causes of Dementia

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Dementing illnesses are typically categorized as irreversible or treatable. The degree to which a particular dementia can be treated varies. The incidence of treatable/reversible dementias is estimated at between 5-20%. The variation maybe due to some disorders which are treatable to a smaller degree being included on some lists but not on others. Also the boundaries between treatable and untreatable are shifting as new drugs emerge offering the hope of even temporary delay of progress or even the potential reversal of symptoms for a period of time.

Irreversible dementias are generally progressive, but the rate at which they worsen (progress) will vary by specific cause and the individual.

Those causes that are either wholly treatable (reversible) or partially treatable are:

  • Delirium -- a condition resulting from a specific temporary conditions such as fever, infection and so on.
  • Brain tumors that can be removed
  • Chronic drug use or alcohol use -- leading to Korsakoff’s Syndrome or vitamin B1 deficiency.
  • Subdural hematomaan -- an accumulation of blood beneath the outer covering of the brain that results from a broken blood vessel, usually as a result of a head injury.
  • Normal pressure hydrocephalus
  • Metabolic disorders -- such as a vitamin B12 deficiency.
  • Hypothyroidism -- a condition that results from low levels of thyroid secretion.
  • Hypoglycemia -- a condition that results from low blood sugar.
  • Depression

    Non-treatable* causes of dementia include:

  • Degenerative neurological diseases -- such as Alzheimer's, Lewy Body dementia, Parkinson's and Huntington's.
  • Vascular disorders -- such as multi-infarct dementia (TIA), which is caused by multiple small strokes in the brain (includes Binswanger’s disease).
  • Infections that affect the central nervous system -- such as HIV dementia complex and Creutzfeldt-Jakob disease.
  • Frontal lobe dementia -- such as Pick’s disease (normally an early onset disorder).
  • AIDS dementia complex
  • Certain types of hydrocephalus -- an accumulation of fluid in the brain that can result from developmental abnormalities, infections, injury, or brain tumors.

    *The idea of untreatable and irreversible is shifting slowly as new medications increase the options available for people with Alzheimer’s, strokes, etc. Our Newsletter will help you keep up-to-date with the latest drug and treatment information.


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